Uma Aryal
Principal Investigator | Purdue Proteomics Facility Director
Dr. Aryal obtained his PhD from Kyushu University, Japan, where he studied biodegradation of aromatic pollutants by the white-rot fungus. During his postdoctoral research, Uma worked on developing analytical methods for MS-based proteomics, including the study of protein post-translational modifications, and the identification of protein complexes. His research goal is to obtain a mechanistic view of cellular pathways and processes using systems-level knowledge. Uma has published more than 120 peer reviewed research and review articles. Dr. Aryal continues working at the interface between biology and proteomics, and is interested in developing new MS-based tools to discover new protein complexes, and protein-protein interactions.
Graduate Students
Rodrigo Mohallem
Rodrigo is a fifth-year PhD candidate in the Department of Comparative Pathobiology. He obtained his B.S. degree from Purdue University, in Biochemistry, Genetics and Cell, Molecular & Developmental Biology, with a minor in Chemistry. His research focuses on global and targeted proteomics approaches to unveil the complex dynamics of the proteome landscape of cells during senescence.
Punyatoya Panda
Punyatoya Panda joined the Aryal lab in January 2022. Her project focuses on elucidating the changes in lipid composition in response to aging. Punya is uncovering the mechanisms behind the regulations in the cellular lipidome, and how they contribute to the senescence phenotype.
Anup Bhusal
Anup Bhusal joined the Department of Comparative Pathobiology in the Fall of 2024, jointly mentored by both Dr. Uma Aryal and Dr. Jing Liu, from the Department of Physics and Astronomy. He focuses on understanding the role of biomolecular condensates in chromatin dynamics, transcription, and genome maintenance. Anup is also interested on the study of misfolded proteins and their clearance in neurodegenerative diseases.
Undergraduate Students
Malyka Ram | Purdue Agricultural and Biological Engineering
Rishabh Kottakota | Purdue Biology
Aryaman Dewan | Promega D.O.O.R.S Scholar | Purdue Biology
Priyanshu Datta Roy | Purdue Agricultural and Biological Engineering
Aarya Sontakke | Purdue Computer Science